Immunochemical methods for consistency testing
This work package aims to
- develop and optimise immunochemical methods for monitoring the consistency of antigen quantity and/or quality throughout the production process,
- investigate whether the assay is suitable for testing vaccines from multiple different manufacturers and
- investigate the extent to which in vitro methods are able to detect antigenic changes relevant to the biological functions of vaccines.
Partners involved
- National Institute for Biological Standards and Control (NIBSC, Work Package Leader)
- Paul-Ehrlich-Institut (PEI)
- Institute for Translational Vaccinology (Intravacc)
- Istituto Superiore di Sanità (ISS)
- Austrian Agency for Health and Food Safety (AGES)
- Scientific Institute of Public Health (WIV-ISP)
- Biomedical Primate Research Centre (BPRC)
- Sanofi Pasteur (SP)
- Zoetis
- Merial
- Boehringer Ingelheim (BI)
- Merck Sharp & Dohme (MSD)
- GlaxoSmithKline Biologicals (GSKBio)