Cell-based assays for consistency testing
In this work package, the aim is the development, optimization and application of cell-based assays that allow in vitro monitoring of parameters linked to the biological function of vaccines (i.e. capability to induce a protective immune response) or their safety (i.e. absence of toxicity).
Partners involved
- National Institute for Public Health and the Environment (RIVM)
- National Institute for Biological Standards and Control (NIBSC)
- Paul-Ehrlich-Institute (PEI)
- Universtiy of Utrecht (UU)
- Unversity Medical Center Groningen (UMCG)
- Institute for Translational Vaccinology (Intravacc, Work Package Leader)
- Istituto Superiore di Sanità (ISS)
- Biomedical Primate Research Centre (BPRC)
- Sanofi Pasteur (SP)
- Zoetis
- Merial
- Boehringer Ingelheim (BI)
- Merck Sharp & Dohme (MSD)
- GlaxoSmithKline Biologicals (GSKBio)