Cell-based assays for consistency testing

In this work package, the aim is the development, optimization and application of cell-based assays that allow in vitro monitoring of parameters linked to the biological function of vaccines (i.e. capability to induce a protective immune response) or their safety (i.e. absence of toxicity).

Partners involved

• National Institute for Public Health and the Environment (RIVM)
• National Institute for Biological Standards and Control (NIBSC)
• Paul-Ehrlich-Institute (PEI)
• Universtiy of Utrecht (UU)
• Unversity Medical Center Groningen (UMCG)
• Institute for Translational Vaccinology (Intravacc, Work Package Leader)
• Istituto Superiore di Sanità (ISS)
• Biomedical Primate Research Centre (BPRC)
• Sanofi Pasteur (SP)
• Zoetis
• Merial
• Boehringer Ingelheim (BI)
• Merck Sharp & Dohme (MSD)
• GlaxoSmithKline Biologicals (GSKBio)