Work Package 4

Multiparametric assays & bioinformatics for consistency testing

The objectives of this work package are:

  • to develop transcriptomics/proteomics technology and identify bacterial biomarkers suitable for characterization of Clostridium tetani seed strains,
  • to develop an alternative for the histamine sensitisation test for Pertussis vaccine safety based on kinome analysis and
  • to develop platform technology and identify biomarkers for the assessment of vaccine quality based on responses of antigen presenting cells to exposure to vaccines/adjuvants in vitro, in support to Work Package 3

Partners involved