European Commission, Joint Research Centre (JRC)

As the European Commission's science and knowledge service, the Joint Research Centre's (JRC) mission is to support EU policies with independent evidence throughout the whole policy cycle. Its work has a direct impact on the lives of citizens by contributing with its research outcomes to a healthy and safe environment, secure energy supplies, sustainable mobility and consumer health and safety.

The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre. As from 2011, ECVAM's tasks are assigned to the European Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM). EURL ECVAM coordinates the validation of alternative methods at the EU level, acts as a focal point for the exchange of information on alternatives, manages database services and ensures that the scientifically validated methods undergo a rapid procedure to gain regulatory acceptance.

Role of JRC in VAC2VAC

The JRC represented by EURL ECVAM will participate in the project as leader of Work Package 5 being responsible for the tasks related to validation. The JRC will contribute to work package 6 with its experience gained in international dissemination, harmonisation and regulatory acceptance.

Partner representatives

Marlies HalderDr Marlies Halder is a Senior Scientist at the European Commission's Joint Research Centre, Directorate F - Health, Consumers and Reference Materials, Chemical Safety and Alternative Methods Unit / European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) in Ispra, Italy. She is responsible for EURL ECVAM's activities on replacement, reduction and refinement related to the quality control of biologicals and environmental toxicity testing of chemicals.

Over the past 10 years, EURL ECVAM promoted the use of the consistency approach for the quality control of vaccines by sponsoring and co-organising three workshops and supporting activities at EPAA level.

"It is encouraging to witness the launch of the VAC2VAC project and eventually put the theory into practice."